Kathryn A. Morton

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The use of computer-assisted diagnosis has become widespread in cardiac nuclear medicine. Quantitative programs are commercially available for ventriculography, phase analysis, and thallium 201 perfusion studies. The goal of these programs is to eliminate interobserver variability by objectively analyzing the studies without causing a loss of accuracy. In(More)
Cancer survivors often relapse due to evolving drug-resistant clones and repopulating tumor stem cells. Our preclinical study demonstrated that terminal cancer patient's lymphocytes can be converted from tolerant bystanders in vivo into effective cytotoxic T-lymphocytes in vitro killing patient's own tumor cells containing drug-resistant clones and tumor(More)
Computer-assisted diagnosis (CAID) is commonly used to evaluate cardiac nuclear medicine studies such as thallium perfusion scans. Part I of this series (Journal of Digital Imaging, Vol 5, No 4, pp 209-222) reviewed the basic theory underlying CAID in nuclear medicine and its use in planar thallium imaging. This review discusses the application of CAID to(More)
C ases are stories with a message. They are not simply narratives for entertainment. They are stories to educate. Humans are story-telling animals. Consequently, the use of cases gives a teacher an immediate advantage; he has the attention of the audience. The best way to start this column is with a glance at the history of case study teaching in academia.(More)
Computer-assisted diagnosis (CAID) is commonly used to evaluate cardiac nuclear medicine studies such as thallium perfusion scans. Part 1 of this series (Journal of Digital Imaging, 5:209-222, 1992) reviewed the basic theory underlying CAID in nuclear medicine and its use in planar thallium imaging. Part 2 discussed the application of CAID to SPECT(More)
Although amyloid deposition remains a marker of the development of Alzheimer's disease, results linking amyloid and cognition have been equivocal. Twenty-five community-dwelling non-demented older adults were examined with (18)F-flutemetamol, an amyloid imaging agent, and a cognitive battery, including an estimate of premorbid intellect and the Repeatable(More)
Hydrogels, polymers and various other composite materials may be used in sensing applications in which the swelling or de-swelling of the material in response to some analyte is converted via a transducer to a measurable signal. In this paper, we analyze models used to predict the swelling behavior of hydrogels that may be used in applications related to(More)
BACKGROUND Metastatic renal cell carcinoma has a poor prognosis and an intrinsic resistance to standard treatment. Sunitinib is an oral receptor tyrosine kinase inhibitor that has been used as a first-line targeted therapy in metastatic renal cell carcinoma. While computed tomography (CT) is currently the gold standard for response assessment in oncological(More)
"What got people out of the trees was something besides thumbs and gadgets. What did it I am convinced, was a warp in the simian brain that made us insatiable for patterns-patterns of sequence, of behavior, of feeling-connections, reasons, causes: stories." Computer modeling of adaptive depression; Modeling manic-depression with symbolic logic; Species(More)
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