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Speech-in-noise intelligibility does not correlate with efferent olivocochlear reflex in humans with normal hearing
Conclusion. According to the presented data, speech-in-noise intelligibility (SI) does not correlate with olivocochlear efferent activity – as measured by contralateral suppression (CS) of distortionExpand
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Immediate versus modified release hydrocortisone in mitotane‐treated patients with adrenocortical cancer
Mitotane induces hepatic CYP3A4 activity, resulting in accelerated cortisol inactivation, and also increases cortisol binding globulin (CBG). Therefore, higher hydrocortisone doses are required inExpand
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Reduction in daily hydrocortisone dose improves bone health in primary adrenal insufficiency.
OBJECTIVE Individuals with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) receive life-long glucocorticoid (GC) replacement therapy. Current daily GC doses are stillExpand
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Prednisolone is associated with a worse bone mineral density in primary adrenal insufficiency
Context Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) receive life-long glucocorticoid (GC) therapy. Daily GC doses are often above the physiologicalExpand
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Continuous rhPTH (1–34) treatment in chronic hypoparathyroidism
Summary Standard treatment of hypoparathyroidism consists of supplementation of calcium and vitamin D analogues, which does not fully restore calcium homeostasis. In some patients, hypoparathyroidismExpand
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BclI polymorphism of the glucocorticoid receptor and adrenal crisis in primary adrenal insufficiency
Context Patients with primary adrenal insufficiency (PAI) or congenital adrenal hyperplasia (CAH) are at a high risk of adrenal crisis (AC). Glucocorticoid sensitivity is at least partiallyExpand