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BACKGROUND As the number of people with Internet access rises, so does the use of the Internet as a potentially valuable source for health information. Insight into patient use of this information and its correlates over time may reveal changes in the digital divide based on patient age and education. Existing research has focused on patient characteristics(More)
BACKGROUND Systemic sclerosis (SSc)-overlap syndromes are a very heterogeneous and remarkable subgroup of SSc-patients, who present at least two connective tissue diseases (CTD) at the same time, usually with a specific autoantibody status. OBJECTIVES To determine whether patients, classified as overlap syndromes, show a disease course different from(More)
OBJECTIVES The aim of this retrospective study was to assess pre- and intraoperative factors leading to neurological complications and early death following repair of acute type A aortic dissection (ATAAD). METHODS There were 122 patients (85 male, age: 58.6 ± 12.5 years) with ATAAD, treated consecutively from August 2003 to August 2010. Pre- and(More)
BACKGROUND Thrombotic microangiopathies (TMA) in adults such as thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) are life-threatening disorders if untreated. Clinical presentation is highly variable and prognostic factors for clinical course and outcome are not well established. METHODS We performed a retrospective(More)
AIMS The impact of type of first medical contact (FMC) in the setting of a guideline conform metropolitan ST-elevation myocardial infarction (STEMI) network providing obligatory primary percutaneous coronary intervention (PCI) is unclear. METHODS AND RESULTS 3,312 patients were prospectively included between 2006 and 2012 into a registry accompanying the(More)
The purpose of this study was to compare approved first-line therapies for patients with multiple myeloma. A systematic literature search for phase III randomized controlled trials (RCTs) comparing first-line chemotherapies approved in Germany and recommended by guidelines at the time of study design was conducted. Random-effects meta-analysis (MA) was used(More)
OBJECTIVE To compare the mortality of patients in a palliative care unit on working days with that on weekends and public holidays. DESIGN Retrospective database study. SETTING Palliative care unit in Germany. POPULATION All admissions to palliative care unit between 1 January 1997 and 31 December 2008. MAIN OUTCOME MEASURE The impact of day type(More)
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