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BACKGROUND Women with the Lynch syndrome (hereditary nonpolyposis colorectal cancer) have a 40 to 60 percent lifetime risk of endometrial cancer and a 10 to 12 percent lifetime risk of ovarian cancer. The benefit of prophylactic gynecologic surgery for women with this syndrome has been uncertain. We designed this study to determine the reduction in the risk(More)
Pervasive medical monitoring has become an ideal alternative to nursing care for elderly people and patients in hospitals. Existing systems using single body-worn sensors are often intrusive and less reliable. By contrast, ubiquitous acoustic sensing techniques can support non-intrusive and robust medical monitoring. In this paper, we describe CoughLoc, a(More)
Osteogenesis imperfecta (OI), also known as brittle bone disease, is a clinically and genetically heterogeneous disorder primarily characterized by susceptibility to fracture. Although OI generally results from mutations in the type I collagen genes, COL1A1 and COL1A2, the relationship between genotype and phenotype is not yet well understood. To provide(More)
Despite the use of newer and more powerful calendar and collaboration tools, the task of scheduling and rescheduling meetings is very time consuming for busy professionals, especially for highly mobile people. Research projects and commercial calendar products have worked since the early 1990s on implementing intelligent meeting organizers to automate(More)
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