Kathleen M. McMullen

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One hundred seventy patients with gastrointestinal carcinoid tumors were treated at Ochsner Clinic from 1958 to 1990. Ninety-four rectal carcinoid tumors were diagnosed and treated during this time. Carcinoid tumors of the rectum represented the most frequent primary site (55 percent), followed by carcinoids of the ileum (12 percent), appendix (12 percent),(More)
BACKGROUND Limited data on the risk of peripherally inserted central venous catheter-associated bloodstream infections (PICC BSIs) in hospitalized patients are available. In 2007, dedicated intravenous therapy nurses were no longer available to place difficult peripheral intravenous catheters or provide PICC care Barnes-Jewish Hospital. OBJECTIVES To(More)
OBJECTIVE The purpose of this study was to determine the effects of a simple low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit. DESIGN Preintervention and postintervention observational study. SETTING Twenty-four bed surgical/trauma/burn intensive care units in an urban university hospital. PATIENTS(More)
BACKGROUND The Centers for Disease Control and Prevention has shifted policy away from using ventilator-associated pneumonia (VAP) and toward using ventilator-associated conditions (VACs) as a marker of ICU quality. To date, limited prospective data regarding the incidence of VAC among medical and surgical ICU patients, the ability of VAC criteria to(More)
An increased rate of Clostridium difficile-associated diarrhea (CDAD) was noted in 2 intensive care units of a university-affiliated tertiary care facility. One unit instituted enhanced environmental cleaning with a hypochlorite solution in all rooms, whereas the other unit used hypochlorite solution only in rooms of patients with CDAD. The CDAD rates(More)
BACKGROUND Manual surveillance for central line-associated bloodstream infections (CLABSIs) by infection prevention practitioners is time-consuming and often limited to intensive care units (ICUs). An automated surveillance system using existing databases with patient-level variables and microbiology data was investigated. METHODS Patients with a positive(More)
BACKGROUND The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been well described; however, few studies have reviewed long-term hospital-wide data. METHODS This retrospective study of adult patients used the first culture per patient per visit positive for MRSA for 1996 to 2005. Isolates were categorized as(More)
The potential to automate at least part of the surveillance process for health care-associated infections was seen as soon as hospitals began to implement computer systems. Progress toward automated surveillance has been ongoing for the last several decades. But as more information becomes available electronically in the healthcare setting, the promise of(More)
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is a virulent organism causing substantial morbidity and mortality in intensive care units. Chlorhexidine gluconate, a topical antiseptic solution, is effective against a wide spectrum of gram-positive and gram-negative bacteria, including MRSA. Objectives To examine the impact of a bathing(More)
Total proteolytic activity and protein synthesis were measured in cell-free extracts of the thymus during its involution in 1-30-week-old C57Bl/6J mice, and in 10-, 12-, 14-, and 24-month-old adult mice of the same strain. The mean specific activity of the proteolytic enzymes exhibited no significant change during involution or throughout the mean life-span(More)