Kathleen F. Miller

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The effect of Mycoplasma gallisepticum (MG) infection or vaccination of Conn. F-strain MG on 45 weeks of egg production was analyzed using production records from 132 flocks of commercial layer hens. The flocks were located in Pennsylvania, and the data were collected for two years. On the average, layers maintained free from infection with MG laid 15.7(More)
Genetic engineering of livestock is expected to have a major effect on the agricultural industry. However, accurate assessment of the consequences of transgene expression is impossible without multigenerational studies. A systematic study of the beneficial and adverse consequences of long-term elevations in the plasma levels of bovine growth hormone (bGH)(More)
Recent research clearly shows that fusion genes can be microinjected into a pronucleus of an ovum and integrate into the pig genome. Animals with such fusion genes are called 'transgenic'. The percentage of injected ova that developed into transgenic pigs varied among experiments from 0.31% to 1.73%. The percentage of transgenic pigs that expressed the(More)
Microdrops of medium under either paraffin or silicone oil are commonly used for culture of early mammalian embryos. Radiolabeled estradiol, progesterone, and androstenedione in drops of medium under oil decreased by 51, 89, and 77%, respectively, after 24-hr incubation. Up to 14% of labeled estradiol moved to another drop of medium by passing through the(More)
Observations of follicular and gonadotrophic changes were conducted on 14 Pony mares for 31-day periods beginning at the penultimate (second last) ovulation and at the last ovulation of the season. There were no main effects or interaction of day or period on the numbers of small follicles (less than 20 mm). Concentrations of FSH, numbers of large follicles(More)
Chimeric genes containing either the mouse transferrin (Trf) enhancer/promoter fused to the structural sequences encoding bovine growth hormone (GH) or the mouse albumin (Alb) enhancer/promoter fused to the gene for human growth hormone-releasing factor (GRF) were microinjected into sheep zygotes. A low percentage of resulting transgenic sheep chronically(More)
Transgenic pigs and sheep have been produced by the microinjection of single-cell zygotes and two-cell ova with linear molecules of mouse metallothionein I (MT) promoter/regulator fused to either the human growth hormone (hGH) or bovine growth hormone (bGH) structural genes. The foreign genes integrated into the chromosomes of 3 of 111 lambs or fetuses and(More)