Kathleen A Fairman

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OBJECTIVE Patients with treatment-resistant schizophrenia commonly receive nonrecommended drug regimens, including antipsychotic polypharmacy, sometimes in lieu of clozapine. This analysis compared utilization and cost outcomes for cohorts of Medicaid beneficiaries treated with clozapine monotherapy and with antipsychotic polypharmacy. METHODS Data were(More)
OBJECTIVE The study examined whether the relationship between the course of antidepressant treatment and the type of prescriber-psychiatrist or nonpsychiatrist-varied by whether a tricyclic antidepressant or a selective serotonin reuptake inhibitor (SSRI) was prescribed. METHODS Pharmacy claims from a nationwide database were analyzed retrospectively. A(More)
Even as you read this, new monsters are being made, new items crafted, and dungeons overflowing with horrible surprises are being designed to test your bravery and intellect. 1 A sk a teenage boy the object of the on-line game Dragon Fable, the topic of the promotional description that appears above, and you will endure several moments of eye rolling(More)
W hen we wrote our March, 2008 editorial in JMCP regarding the lack of evidence of value in value-based insurance design (VBID), 1 we correctly anticipated that those working in the " trenches " of managed care pharmacy would appreciate an objective evaluation of the evidence about prescription drug cost-sharing. What we did not anticipate was a query we(More)
BACKGROUND For patients with multiple sclerosis (MS), previous research identified key disease sequelae as important cost drivers and suggested that among users of disease-modifying drugs (DMDs) in 2004, DMDs represented 73% of the total cost of care. More recent studies were limited to incident disease/treatment and/or excluded DMDs from cost estimates. To(More)
I t was October 25, 1986. Game 6 of the World Series between the New York Mets and the Boston Red Sox was tied in the bottom of the 10th inning, with 2 outs and 1 runner on base. The Mets' Mookie Wilson hit a routine grounder in the direction of first baseman Bill Buckner, who bent down to scoop it up. But in one of the most infamous incidents in sports(More)
T ell the patient that the pill contains nothing but sugar, and there is no pain relief; tell him (falsely) that it contains a powerful analgesic, and the perceived level of pain falls. [Defendants insist that a] product that confers this benefit cannot be excluded from the market … just because they told the lies necessary to bring the effect about … [But](More)
1 Khandker et al. introduce their study of antidepressant therapy class switching, published in this issue of JMCP, with the point that " between 30% and 50% of patients with major depression fail to respond to an initial course of antidepres-sant therapy " despite a wide range of antidepressant drug therapy options. 2 The high failure rate for(More)
I n the November/December 2006 issue of JMCP, Watkins et al. reported the estimated value of exenatide in treating obese patients with type 2 diabetes over a 30-year time horizon, as calculated using the Center for Outcomes Research Diabetic Model, a validated Markov model that predicts clinical and economic end points over time horizons up to 100 years in(More)
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