Katherine Lily Wu

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Bisphenol A (BPA) exposure has been documented in pregnant women, but consequences for development are not yet widely studied in human populations. This review presents research on the consequences for offspring of BPA exposure during pregnancy. Extensive work in laboratory rodents has evaluated survival and growth of the conceptus, interference with(More)
Trichloroethylene (TCE), a commonly used industrial degreasing solvent and environmental toxicant, reduces rat oocyte fertilizability by an incompletely understood mechanism. Previous evidence implicated cytochrome P450 dependent oxidation of TCE. The current study investigated a second pathway, glutathione conjugation using S-(1,2-dichlorovinyl)-L-cysteine(More)
Exposure to trichloroethylene (TCE, an environmental toxicant) reduced oocyte fertilizability in the rat. In vivo, TCE may be metabolized by cytochrome P450 dependent oxidation or glutathione conjugation in the liver or kidneys, respectively. Cytochrome P450 dependent oxidation is the higher affinity pathway. The primary isoform of cytochrome P450 to(More)
A novel nomenclature for the hypervariable microsatellite DNA, APOAI1 locus, is proposed. The complex nature of the repeat unit in this locus results in alleles separated by a single base. Polymerase chain reaction (PCR) products amplified from this locus were separated by single-strand conformation polymorphism (SSCP) electrophoresis. All the(More)
The Deep Extragalactic Evolutionary Probe (DEEP) is a series of spectroscopic surveys of faint galaxies, targeted at understanding the properties and clustering of galaxies at redshifts z ∼ 1. We present the redshift catalog of the DEEP 1 Groth Strip pilot phase of this project, a Keck/LRIS survey of faint galaxies in the Groth Survey Strip imaged with HST(More)
As part of the Deep Extragalactic Evolutionary Probe (DEEP) survey, a sample of 190 field galaxies (I814 ≤ 23.5) in the “Groth Survey Strip” has been used to analyze the magnitude-size relation over the range 0.1 < z < 1.1. The survey is statistically complete to this magnitude limit. All galaxies have photometric structural parameters, including bulge(More)
Exposure of female rats to trichloroethylene (TCE), an environmental toxicant commonly found in ground and surface waters throughout the United States, reduces the fertilizability of oocytes produced by these females compared with oocytes from control females. Localization of cytochrome P450 2E1 and glutathione s-transferase alpha, TCE-metabolizing enzymes,(More)
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