Katherine H Chau | Semantic Scholar

Mediator Subunit Gal11p/MED15 Is Required for Fatty Acid-dependent Gene Activation by Yeast Transcription Factor Oaf1p*

J. Thakur, H. Arthanari, Fajun Yang, Katherine H Chau, G. Wagner, A. Näär
Biology
Journal of Biological Chemistry
13 February 2009

Evidence is provided for an ancient and essential role of a Mediator co-activator subunit in regulation of fatty acid metabolism by nuclear receptor-like transcription factors in eukaryotes.

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The book of opposites: the role of the nuclear receptor co-regulators in the suppression of epidermal genes by retinoic acid and thyroid hormone receptors.

Sang H. Jho, C. Vouthounis, M. Tomic-Canic
Biology
The Journal of investigative dermatology
1 May 2005

It is found that in the context of specific keratin RE (KRE), co-activators and histone acetylase become co-repressors of the RA/T3 receptors in the presence of their respective ligands, thus exerting intrinsic tissue specificity.

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