Katherine E. R. Stagliano

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Unlike what is seen for other tumor suppressors, in the majority of human carcinomas with p53 mutations, a protein with one amino acid substitution is overexpressed, suggesting the existence of a selection pressure for maintaining expression of the This also is perhaps indicative of an active role played by p53 mutants in oncogenesis and follows the(More)
Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United States. A well recognized disparity by race in both incidence and survival outcome exists for this cancer. Specifically Caucasians are about two times more likely to develop endometrial cancer than are African-Americans. However, African-American women are more likely to(More)
A potent T cell response is an important component of durable anti-tumor immunity. The quality of the T cell response can, in-part, be measured by the avidity of the T cell for its tumor antigen-expressing target. While convention suggests that raising the avidity of the responding T cells may make for a more potent anti-tumor immune response, the threshold(More)
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