Katherine C. Palozola

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The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F(More)
The transition of Drosophila third instar larvae from feeding, photo-phobic foragers to non-feeding, photo-neutral wanderers is a classic behavioral switch that precedes pupariation. The neuronal network responsible for this behavior has recently begun to be defined. Previous genetic analyses have identified signaling components for food and light sensory(More)
During mitosis, the genome is silent. When cells exit mitosis and re-enter the cell cycle, how does the tran-scriptional program of a differentiated cell become reactivated faithfully and in a timely manner? We previously found that in undifferentiated progenitor cells in the early embryo, the competence to activate transcription-ally silent genes is(More)
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