Katharine Kinsman

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Studies treating adenocarcinoma of the pancreas with gemcitabine alone or in combination with a doublet have demonstrated modest improvements in survival. Recent reports have suggested that using the triple-drug regimen FOLFIRINOX can substantially extend survival in patients with metastatic disease. We were interested in determining the clinical benefit of(More)
After undergoing high-dose chemotherapy and autologous bone marrow transplantation, a patient developed fatal disseminated infection due to varicella-zoster virus (VZV) with no coincident skin lesions. This article describes this unusual case and briefly reviews the English-language literature on the abdominal presentation of VZV infection as well as that(More)
We have generated chromosome 3-specific recombinant libraries in both lambda and cosmid cloning vectors starting with somatic cell hybrids (hamster/human) containing either an intact chromosome 3 or a chromosome 3 with an interstitial deletion removing 75% of long-arm sequences. The libraries contained between 2 X 10(5) and 5 X 10(6) independent(More)
Purpose As a result of the leucovorin shortage, we switched from BSA-adjusted to low fixed-dose leucovorin in patients with colon cancer receiving fluorouracil-containing therapy. Methods A retrospective, pilot study of adults receiving intravenous leucovorin as part of a fluorouracil-containing treatment was conducted including individuals with stage II or(More)
Purpose Hyperhydration and urinary alkalinization is implemented with all high-dose (HD)-methotrexate infusions to promote excretion and prevent precipitation of methotrexate in the renal tubules. Our institution utilized enteral alkalinizing agents (sodium bicarbonate tablets and sodium citrate/citric acid solution) to alkalinize the urine of patients(More)
Oxybutynin (OXY) used in combination with clean intermittent catheterisation (CIC), has been the first-line medication for treatment of neurogenic bladder dysfunction over the past two decades. The efficacy of oral OXY in treatment of neurogenic bladder has been demonstrated in several studies. OXY has been shown to increase the maximum bladder capacity,(More)
Background The Chesapeake-Potomac Spina Bifida Association (CPSBA) conducted a survey of individuals with spina bifida (SB) in Maryland during the first half of 2004 in order to assess their current status and unmet needs. The survey was sponsored by the Maryland State Office of Genetics and Children with Special Health Care Needs (OGCSHCN). The findings of(More)
Address: 1Departments of Neuropsychology, Kennedy Krieger Institute, 2Departments of Behavior Psychology, Kennedy Krieger Institute, 3Departments of the Center for Spina Bifida and Related Conditions, Kennedy Krieger Institute, 4Departments of Psychiatry, Johns Hopkins University School of Medicine, 5Departments of Pediatrics, Johns Hopkins University(More)
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