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  • William Harmon Norton, Katharina Stumpenhorst, +5 authors Laure Bally-Cuif
  • Biology, Medicine
  • The Journal of neuroscience : the official…
  • 2011 (First Published: 28 September 2011)
  • Behavioral syndromes are suites of two or more behaviors that correlate across environmental contexts. The aggression-boldness syndrome links aggression, boldness, and exploratory activity in a novelContinue Reading
  • Elizabeth M. Tunbridge, Graham Dunn, +6 authors Daniel Freeman
  • Psychology, Medicine
  • Journal of psychopharmacology
  • 2015 (First Published: 1 November 2015)
  • Cannabis use can induce cognitive impairments and psychotic experiences. A functional polymorphism in the catechol-O-methyltransferase (COMT) gene (Val158Met) appears to influence the immediateContinue Reading
  • Elizabeth M. Tunbridge, Alexa Huber, Sarah M. Farrell, Katharina Stumpenhorst, Philip J Harrison, M. E. Walton
  • Psychology, Medicine
  • CNS & neurological disorders drug targets
  • 2012 (First Published: 1 May 2012)
  • Catechol-O-methyltransferase (COMT) catabolises dopamine and is important for regulating dopamine levels in the prefrontal cortex. Consistent with its regulation of prefrontal cortex dopamine, COMTContinue Reading
  • Chris Barkus, Clio Korn, +9 authors Elizabeth M. Tunbridge
  • Psychology, Medicine
  • Neuropsychopharmacology
  • 2016 (First Published: 1 December 2016)
  • Catechol-O-methyltransferase (COMT) modulates dopamine levels in the prefrontal cortex. The human gene contains a polymorphism (Val158Met) that alters enzyme activity and influences PFC function. ItContinue Reading