Katharina Stahl

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Thiamine is metabolized into an essential cofactor for several enzymes. Here we show that oxythiamine, a thiamine analog, inhibits proliferation of the malaria parasite Plasmodium falciparum in vitro via a thiamine-related pathway and significantly reduces parasite growth in a mouse malaria model. Overexpression of thiamine pyrophosphokinase (the enzyme(More)
The introduction of embedded systems equipped with FPGA having a GPP contained inside them (Reconfigurable SoC (RSoC)) create a lot of challenges to OS for resource management. In distributed RSoCs, different applications may run on different RSoCs with variant resource requirements. Due to the variety of applications, a continuous change in demands from OS(More)
Upcoming interlinked embedded systems will be confronted with unexpectedly changing environments, which makes online adaptation without manual interference necessary. There is a need for appropriate system architectures and novel design approaches. In this paper, we discuss general concepts of self-adaptive real-time systems. Furthermore, specific system(More)
Autonomous adaptation in self-adapting embedded real-time systems introduces novel risks as it may lead to unforeseen system behavior. An anomaly detection framework integrated in a real-time operating system can ease the identification of such suspicious novel behavior and, thereby, offers the potential to enhance the reliability of the considered self-x(More)
In self-adapting embedded real-time systems, operating systems and software provide mechanisms to self-adapt to changing requirements. Autonomous adaptation decisions introduce novel risks as they may lead to unforeseen system behavior that could not have been specified within a design-time model. However, as part of its functionality the operating system(More)