Katharina Elsaesser

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Mitochondrial demise is a key feature of progressive neuronal death contributing to acute and chronic neurological disorders. Recent studies identified a pivotal role for the BH3-only protein B-cell lymphoma-2 interacting domain death antagonist (Bid) for such mitochondrial damage and delayed neuronal death after oxygen-glucose deprivation,(More)
PURPOSE Increased intraocular pressure (IOP) is a frequent complication after penetrating keratoplasty and can be due to reduced trabecular meshwork outflow facility. Descemet stripping endothelial keratoplasty (DSEK) is a lamellar technique for replacing pathologic corneal endothelium and may be associated with a lower risk of postoperative IOP rise. In a(More)
Neuronal cell death is the main cause behind the progressive loss of brain function in age-related neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Despite the differing etiologies of these neurological diseases, the underlying neuronal damage is triggered by common mechanisms such as oxidative stress, impaired calcium homeostasis,(More)
The purpose of this study was to analyse and compare the visual and refractive results after DSEK with manual donor dissection and DSAEK with microkeratome-assisted donor dissection in a retrospective unmasked case control study. DSEK was performed in 15 eyes of 15 patients (74.9 ± 7.9 years; 4♂, 11♀). DSAEK was performed in 15 eyes of 15 patients (76.5 ±(More)
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