Katharina Büttner

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The exosome, a large multisubunit complex with exoribonucleic activity, emerges as the central 3' RNA degradation and processing factor in eukaryotes and archaea. But how are the many RNA substrates of the exosome degraded in a processive, yet controlled manner? Recent functional and structural progress shows that the exosome is a macromolecular cage, where(More)
  • Holger Von Moeller, Gutachter, Elena Conti, Patrick Cramer, Meinen Eltern, Zusammenfassung Die +29 others
  • 2009
Diese Dissertation wurde selbständig, ohne unerlaubte Hilfe erarbeitet. Abstract The hallmark of eukaryotic evolution was the development of the nucleus in cells. This compartmentalization requires the nucleocytoplasmic transport of thousands of molecules. The gate into and out of the nucleus is the nuclear pore complex (NPC). One of the molecules that(More)
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