Katerina Troshina

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This paper presents a method for automatic reconstruction of polymorphic class hierarchies from the assembly code obtained by compiling a C++ program. If the program is compiled with run-time type information (RTTI), class hierarchy is reconstructed via analysis of RTTI structures. In case RTTI structures are missing in the assembly, a technique based on(More)
CD44 is a polymorphic family of immunologically related integral membrane glycoproteins associated with cell matrix adhesion, lymphocyte activation and targeting, and tumor growth and metastasis. We studied CD44 expression in 114 formalin-fixed paraffin-embedded thyroid tumors using the A3D8 anti-human CD44 monoclonal antibody. Sixty-five of 67 papillary(More)
CD44 is a polymorphic family of immunologically related cell surface proteoglycans and glycoproteins implicated in cell-cell and cell-matrix adhesion interactions, lymphocyte activation and homing, cell migration, and tumor metastasis. CD44 exists as a standard form and as multiple isoforms, each generated by alternative splicing of up to 10 variant exons(More)
Papillary thyroid cancer is the most common endocrine malignancy. Of all solid cancers presenting in adults, papillary thyroid cancer generally carries the best long-term prognosis. However, very little is understood about the molecular pathogenesis of this neoplasm. We recently hypothesized that increased nuclear levels of MDM2 protein might occur in(More)
The tumor suppressor protein, p53, protects somatic cells against the accumulation of genomic alterations. Cells harboring mutant or inactivated wild-type p53 protein are at risk for the development of genomic instability. Nuclear accumulation of p53 protein is associated with the stepwise dedifferentiation of papillary carcinoma. We asked whether nuclear(More)
This paper presents a method for automatic reconstruction of high-level composite types during decompilation of C programs from assembly code. The proposed method is based on expressing memory access operations as pairs (base+offset), then building sets of equivalence for all memory access bases used in the program and accumulating sets of offsets for all(More)
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