Kate Doherty

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1. In RAW 264.7 murine macrophages and rat aortic smooth muscle (RASM) cells lipopolysaccharide (LPS) alone or in combination with interferon gamma (IFN gamma) or forskolin, respectively, stimulated the expression of the 130 kDa inducible isoform of nitric oxide synthase (iNOS) in both a time- and concentration-dependent manner. 2. Incubation with the(More)
Investigations of the cytotoxic activity of T cells induced following one or two intraperitoneal doses of live Salmonella revealed that cytotoxicity was restricted to the Lyt-2+ T-cell subset and was enhanced following secondary infection with Salmonella. Initial studies using the lectin-dependent cellular cytotoxicity (LDCC) assay detected Lyt-2+ cytotoxic(More)
Intraperitoneal injection of (BALB/c x C57BL/6) F1 mice with live, but not killed Salmonella enteritidis 11RX (11RX) induced T cells in the spleen and peritoneal cavity which were able to proliferate in vitro in response to two different forms of 11RX antigens. The majority of cells which proliferated were L3T4+ T cells and most of the response was(More)
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