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Levels of tumor necrosis factor-alpha (TNF-alpha) are increased in the brain in Alzheimer's disease (AD). The TNF-alpha/TNF-R signaling pathways involve complex interactions between several proteins, including TNF-receptor-associated factor-2 (TRAF-2). We have examined the distribution and levels of TRAF-2 in AD and control brains and also whether single(More)
A plaque-forming lambdapolA phage was isolated from a population of transducing phage made in vitro from Escherichia coli DNA and a phage vector digested with restriction endonuclease HindIII. Amber mutations, in genes whose products are necessary for late protein synthesis (Q) and cell lysis (S), were crossed into the lambdapolA phage. Infection of either(More)
Major gene resistance to leaf scald caused by Rhynchosporium commune is readily detected in barley seedlings. Screening of barley lines in this manner has been used to identify and map the presence of several such major genes. Similar detection systems have not been possible for minor genes, detection of which has come from field evaluation of plants at(More)
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