Katarzyna Wiktorska

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1011 Review – The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs. 1038 Review – Role of the SOCS in monocytes/macro-phages-related pathologies. Are we getting closer to a new pharmacological target? Krzysztof 1055 Review – 11>-Hydroxysteroid dehydrogenase type 1: potential therapeutic target for metabolic syndrome. 1066(More)
Multiple in vitro tests are widely applied to assess the anticancer activity of new compounds, including their combinations and interactions with other drugs. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay is one of the most commonly used assays to assess the efficacy and interactions of anticancer agents. However, it can be(More)
Isothiocyanates, among which alyssin is counted, are the compounds that have proved chemopreventive properties and the ability to induce the 2 and the 3 detoxification phase by affecting the transcription factor nuclear erythroid 2-related factor (Nrf2). Having a positive effect on the human body, these compounds are used as dietary supplements. Because of(More)
Porphyrin photosensitizers tend to localize in mitochondria. The depolarization of mitochondrial membrane is one of the early stages of apoptosis and Laser Scanning Fluorescence Microscopy allows to determine changes in transmembrane mitochondrial potential under influence of PDT depending on the kind of photosensitizer (PP(Arg)(2), Hp(Arg)(2)), the energy(More)
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