Katarzyna Urbanska

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In HIV patients, antiretroviral medications trigger metabolic abnormalities, including insulin resistance. In addition, the inflammatory cytokine tumor necrosis factor-α (TNFα), which is elevated in human immunodeficiency virus encephalitis (HIVE), also induces insulin resistance and inflicts neuronal damage in vitro. In differentiated PC12 cells and rat(More)
BACKGROUND Glioblastomas are characterized by rapid cell growth, aggressive CNS infiltration, and are resistant to all known anticancer regimens. Recent studies indicate that fibrates and statins possess anticancer potential. Fenofibrate is a potent agonist of peroxisome proliferator activated receptor alpha (PPARalpha) that can switch energy metabolism(More)
The insulin-like growth factor-1 receptor (IGF-IR) and the human polyomavirus JCV protein, T-antigen cooperate in the transformation of neuronal precursors in the cerebellum, which may be a contributing factor in the development of brain tumors. Because it is not clear why T-antigen requires IGF-IR for transformation, we investigated this process in neural(More)
Redirection of T lymphocytes against tumor antigens can induce dramatic regression of advanced stage malignancy. The use of bispecific antibodies (BsAbs) that bind both the T-cell receptor (TCR) and a target antigen is one promising approach to T-cell redirection. However, BsAbs indiscriminately bind all CD3+ T-cells and trigger TCR activation in the(More)
  • Ankit Raj Mathur, Felix Toran, Katarzyna Urbanska, Miroslav Houdek, Petr Bares, Sisnet +6 others
  • 2012
BIOGRAPHY Ankit Raj Mathur obtained his MSc in Aerospace Communication Systems from ENST Telecom Paris / ISAE Supaero (France). Since 2004, he is working as a System Engineer in the ESA GNSS Regional Augmentation Systems Division in Toulouse, France. He has been involved in many projects related to EGNOS performance, SISNeT and EMS. Dr. Félix Torán holds a(More)
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