Katarzyna Nazimek

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Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten application produce a suppressive component that inhibits the action of the effector T cells that mediate contact sensitivity reactions. We recently re-investigated this phenomenon in an immunological system. CD8+ T lymphocyte-derived exosomes transferred suppressive(More)
Soon after the discovery of T suppressor cells by Gershon in 1970, it was demonstrated that one subpopulation of these lymphocytes induced by i.v. hapten injection suppresses contact sensitivity response mediated by effector CD4+ or CD8+ T cells in mice through the release of soluble T suppressor factor (TsF) that acts antigen specifically. Our experiments(More)
BACKGROUND Our experiments were aimed to test the influence of treatment with different opioids (morphine, fentanyl, methadone) on the humoral and cell-mediated immune responses. METHODS Mice were treated intraperitoneally (ip) with opioids for several days and next either immunized with sheep red blood cells (SRBC) to test the antibody production or(More)
1011 Review – The multidrug transporter P-glycoprotein in pharmacoresistance to antiepileptic drugs. 1038 Review – Role of the SOCS in monocytes/macro-phages-related pathologies. Are we getting closer to a new pharmacological target? Krzysztof 1055 Review – 11>-Hydroxysteroid dehydrogenase type 1: potential therapeutic target for metabolic syndrome. 1066(More)
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