• Publications
  • Influence
Fibronectin remodelling: cell-mediated regulation of the microenvironment.
The biophysical, mechanical and chemical characteristics of extracellular matrixes influence many cellular functions to control tissue homoeostasis and drive progression of cancer and inflammatoryExpand
  • 13
  • 2
Epithelial ovarian cancer-induced angiogenic phenotype of human omental microvascular endothelial cells may occur independently of VEGF signaling.
Epithelial ovarian cancer (EOC) metastasizes transcoelomically to the peritoneum and omentum, and despite surgery and chemotherapy, recurrent disease is likely. Metastasis requires the induction ofExpand
  • 31
  • 1
Hydrogen sulfide in cell signaling, signal transduction, cellular bioenergetics and physiology in C. elegans.
Hydrogen sulfide (H2S), long viewed as a toxic gas and environmental hazard, is emerging as a biological mediator with remarkable physiological and pathophysiological relevance. H2S is now viewed asExpand
  • 20
  • 1
PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis
Basolateral polymerization of cellular fibronectin (FN) into a meshwork drives endothelial cell (EC) polarity and vascular remodelling. However, mechanisms coordinating α5β1 integrin-mediatedExpand
  • 38
  • 1
  • PDF
Synthesis and antiproliferative properties of ibuprofen-oligo(3-hydroxybutyrate) conjugates.
Synthesis of novel conjugates of the non-steroidal anti-inflammatory drug - ibuprofen with nontoxic oligo(3-hydroxybutyrate) (OHB) is described. Presented results indicate that anionic ring-openingExpand
  • 38
Retinopathy in diabetes.
With the incidence, and prevalence of diabetes mellitus increasing worldwide, diabetic retinopathy is expected to reach epidemic proportions. The aim of this chapter is to introduce diabeticExpand
  • 10
Epithelial Ovarian Cancer- Induced Angiogenic Phenotype of Human Omental Microvascular Endothelial Cells May Occur Independently
Epithelial ovarian cancer (EOC) metastasizes transcoelomically to the peritoneum and omentum, and despite surgery and chemotherapy, recurrent disease is likely. Metastasis requires the induction ofExpand
  • 1
Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk
Crosstalk between adhesion and growth factor receptors plays a critical role in tissue morphogenesis and repair, and aberrations contribute substantially to neoplastic disease. However, theExpand
  • 1
Epithelial Ovarian Cancer – Induced Angiogenic Phenotype of Human Omental Microvascular Endothelial Cells May Occur Independently of VEGF Signaling 1 , 2
Epithelial ovarian cancer (EOC) metastasizes transcoelomically to the peritoneum and omentum, and despite surgery and chemotherapy, recurrent disease is likely. Metastasis requires the induction ofExpand