Katarzyna Chwalczuk

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The aim of this study was to evaluate the effects of chronic astemizole and ketotifen administration on the anticonvulsant activity of antiepileptic drugs against maximal electroshock-induced convulsions in mice. Adverse effects were evaluated in the chimney test (motor performance) and passive avoidance task (long-term memory). Brain and plasma levels of(More)
BACKGROUND Methylxanthine derivatives (theophylline, caffeine), nonselective antagonists of adenosine receptors, impair the anticonvulsant activity of antiepileptic drugs in experimental models of epilepsy. THE AIM OF THE STUDY To answer a question whether the selective antagonist of adenosine A1 receptors, 8-cyclopentyl-1,3-dipropylxanthine (CPX), shares(More)
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