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  • Koichi Tabeta, Philippe Georgel, +10 authors Bruce Beutler
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 2004 (First Publication: 9 March 2004)
  • Several subsets of dendritic cells have been shown to produce type I IFN in response to viral infections, thereby assisting the natural killer cell-dependent response that eliminates the pathogen.Expand
  • Kasper Hoebe, Edith M. Janssen, +4 authors Bruce Beutler
  • Biology, Medicine
  • Nature Immunology
  • 2003 (First Publication: 1 December 2003)
  • Both lipopolysaccharide (LPS) and double-stranded RNA (dsRNA) are adjuvants for the adaptive immune response, inducing upregulation of costimulatory molecules (UCM) on antigen-presenting cells. Trif,Expand