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Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2.
- Karyn M. Schmidt, D. M. Wolfe, Barbara Stiller, D. Pearce
- Biology, Medicine
- Biochemical and biophysical research…
- 29 May 2009
The Saccharomyces cerevisiae gene YPK9 encodes a putative integral membrane protein which is 58% similar and 38% identical in amino acid sequence to the human lysosomal P(5B) ATPase ATP13A2.… Expand
Air proteins control differential TRAMP substrate specificity for nuclear RNA surveillance.
RNA surveillance systems function at critical steps during the formation and function of RNA molecules in all organisms. The RNA exosome plays a central role in RNA surveillance by processing and… Expand
A comparison of predictive equations of energy expenditure and measured energy expenditure in critically ill patients.
PURPOSE Multiple equations exist for predicting resting energy expenditure (REE). The accuracy of these for estimating energy requirements of critically ill patients is not clear, especially for… Expand
Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity
The advent of high‐throughput sequencing technologies has revealed that pervasive transcription generates RNAs from nearly all regions of eukaryotic genomes. Normally, these transcripts undergo rapid… Expand
Analysis of Non-Typeable Haemophilous influenzae VapC1 Mutations Reveals Structural Features Required for Toxicity and Flexibility in the Active Site
- Brooke Hamilton, Alexander Manzella, Karyn M. Schmidt, V. DiMarco, J. Butler
- Biology, Medicine
- PloS one
- 12 November 2014
Bacteria have evolved mechanisms that allow them to survive in the face of a variety of stresses including nutrient deprivation, antibiotic challenge and engulfment by predator cells. A switch to… Expand
Structural analysis of VapC1 mutations.
VapC1 mutations cause a spectrum of toxicity defects.
BEFORE THE SCIENCE ADVISORY BOARD - ETHYLENE OXIDE CARCINOGENICITY COMMENTS OF THE ETHYLENE OXIDE/ETHYLENE GLYCOLS PANEL ON EPA'S DRAFT EVALUATION OF CARCINOGENICITY OF ETHYLENE OXIDE ADDRESSING THE…
Rohm & Hass Was Right: Recovery of Government Oversight Costs in Private Party Response Actions
- Karyn M. Schmidt
Pyrrole-imidazole Polyamides : Artificial Genetic Switches for Therapeutic Gene Modulation
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