Karyn E Chappell

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BACKGROUND AND PURPOSE Magic angle effects are well recognized in MR imaging of tendons and ligaments, but have received virtually no attention in MR neurography. We investigated the hypothesis that signal intensity from peripheral nerves is increased when the nerve's orientation to the constant magnetic induction field (B(0)) approaches 55 degrees (the(More)
Performing magnetic resonance investigations in a paediatric population can be difficult; image acquisition is commonly complicated by movement artefact and non-compliance. Sedation is widely used for clinically indicated investigations, but there is controversy when used for research imaging. Over a 10-year period we have performed whole body MRI on over(More)
PURPOSE Normal adult cortical bone has a very short T(2) and characteristically produces no signal with pulse sequence echo times (TEs) routinely used in clinical practice. We wished to determine whether it was possible to use ultrashort TE (UTE) pulse sequences to detect signal from cortical bone in human subjects and use this signal to characterise this(More)
PURPOSE To assess the feasibility of imaging the liver in volunteers and patients with ultrashort echo time (UTE) pulse sequences. MATERIALS AND METHODS Seven normal controls as well as 12 patients with biopsy-proven generalized liver disease and three patients with focal disease were examined using pulse sequences with initial TEs of 0.08 msec followed(More)
OBJECTIVE Infants born to mothers with gestational diabetes mellitus (GDM) are at greater risk of later adverse metabolic health. We examined plausible candidate mediators, adipose tissue (AT) quantity and distribution and intrahepatocellular lipid (IHCL) content, comparing infants of mothers with GDM and without GDM (control group) over the first 3(More)
PURPOSE To investigate the three-dimensional (3D) fast-recovery fast spin-echo accelerated (FRFSE-XL) sequence as a new application for measuring the intraorbital optic nerve (ION) mean cross-sectional area in vivo and to determine its value within a commonly used high resolution imaging protocol. MATERIALS AND METHODS The entire ION was scanned in nine(More)
PURPOSE To assess the values of pulse sequences with ultrashort echo times (0.08 msec) for detecting and characterizing periosteum. MATERIALS AND METHODS Two normal volunteers aged 33 and 58 years and 12 patients aged seven to 55 years were studied. A total of 10 of the patients had contrast enhancement with intravenous Gadodiamide. Two ovine tibias were(More)
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