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- Sheryl Lynch, Karthik Mukundakrishnan, M. R. Benoit, Portonovo S. Ayyaswamy, Angabin Matin
- Applied and environmental microbiology
- 2006

Bacterial biofilms cause chronic diseases that are difficult to control. Since biofilm formation in space is well documented and planktonic cells become more resistant and virulent under modeledâ€¦ (More)

- Karthik Mukundakrishnan, Portonovo S. Ayyaswamy, David M. Eckmann
- Journal of biomechanical engineering
- 2009

Mechanisms governing endothelial cell (EC) injury during arterial gas embolism have been investigated. Such mechanisms involve multiple scales. We have numerically investigated the macroscale flowâ€¦ (More)

- Karthik Mukundakrishnan, Shaoping Quan, David M. Eckmann, Portonovo S. Ayyaswamy
- Physical review. E, Statistical, nonlinear, andâ€¦
- 2007

The wall effects on the axisymmetric rise and deformation of an initially spherical gas bubble released from rest in a liquid-filled, finite circular cylinder are numerically investigated. The bulkâ€¦ (More)

- Karthik Mukundakrishnan, Portonovo S. Ayyaswamy, David M. Eckmann
- Physical review. E, Statistical, nonlinear, andâ€¦
- 2008

We have numerically investigated the axisymmetric motion of a finite-sized nearly occluding air bubble through a shear-thinning Casson fluid flowing in blood vessels of circular cross section. Theâ€¦ (More)

- Tatiana Swaminathan, Karthik Mukundakrishnan, Portonovo S. Ayyaswamy, David M. Eckmann
- Journal of fluid mechanics
- 2010

We present detailed results for the motion of a finite sized gas bubble in a blood vessel. The bubble (dispersed phase) size is taken to be such as to nearly occlude the vessel. The bulk medium isâ€¦ (More)

- Adam M. Zahm, Michael A Bucaro, +4 authors Karthik Mukundakrishnan
- American journal of physiology. Cell physiology
- 2010

Whereas recent work has demonstrated the role of oxygen tension in the regulation of skeletal cell function and viability, the microenvironmental oxemic status of bone cells remains unknown. In thisâ€¦ (More)

- Michael A Bucaro, Jolanta Fertala, +5 authors Makarand V. Risbud
- Annals of the New York Academy of Sciences
- 2004

Studies were performed to evaluate the effects of modeled microgravity on the induction of osteoblast apoptosis. MC3T3-E1 osteoblast-like cells were cultured in alginate carriers in the NASA-approvedâ€¦ (More)

We have numerically investigated the interaction dynamics between two rigid spherical particles moving in a fluid-filled cylinder that is rotating at a constant speed. The cylinder rotation is aboutâ€¦ (More)

- Karthik Mukundakrishnan, David M. Eckmann, Portonovo S. Ayyaswamy
- Annals of the New York Academy of Sciences
- 2009

Intravascular gas embolism may occur with decompression in space flight, as well as during cardiac and vascular surgery. Intravascular bubbles may be deposited into any end organ, such as the heartâ€¦ (More)

- Sharat Prasad, Yun Yun Lu, Shawn Harwood, Karthik Mukundakrishnan, Martin Sanchez Rocha
- 2011

SUMMARY Fluid-structure interaction between incompressible fluids and compliant structures pose a significant numerical challenge in various industrial applications. One such application is inâ€¦ (More)