Karsten H. Weylandt

Learn More
A large body of evidence has emerged over the past years to show the critical role played by inflammation in the pathogenesis of several diseases including some cardiovascular, neoplastic, and neurodegenerative diseases, previously not considered inflammation-related. The anti-inflammatory action of ω-3 polyunsaturated fatty acids (PUFAs), as well as their(More)
The role of non-steroidal anti-inflammatory drugs in inflammatory bowel disease is controversial, as they have been implicated in disease aggravation. Different from other cyclooxygenase inhibitors, acetylsalicylic acid (ASA) enhances the formation of anti-inflammatory and proresolution lipoxins derived from arachidonic acid as well as resolvins from(More)
Enzymatically oxygenated lipid products derived from omega-3 and omega-6 fatty acids play an important role in inflammation dampening. This study examined the anti-inflammatory effects of n-6 docosapentaenoic acid-derived (17S)-hydroxy-docosapentaenoic acid (17-HDPAn-6) and (10,17S)-dihydroxy-docosapentaenoic acid (10,17-HDPAn-6) as well as n-3(More)
Almost forty years ago, it was first hypothesized that an increased dietary intake of omega-3 polyunsaturated fatty acids (PUFA) from fish fat could exert protective effects against several pathologies. Decades of intense preclinical investigation have supported this hypothesis in a variety of model systems. Several clinical cardiovascular studies(More)
While still a controversial topic, the omega-3 fatty acids as subject of research have come of age, particularly in recent years. They have made their way from being simple nutrition components, through possibly some exaggerations nominating them as universal tool to improve human health, to being the object of research in a wide variety of preclinical(More)
The possibility of health benefits associated with dietary omega-3 polyunsaturated fatty acids (í µí¼”-3 PUFAs) has been described for several chronic conditions, including cardio-vascular, neurodegenerative, and neoplastic diseases. A large body of evidence has emerged over the past years to show the critical role played by inflammation in the pathogenesis(More)
  • 1