Karsten Dalsgaard

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An aqueous extract of the saponin drugQuillaja saponaria Molina was separated by a combination of gel exclusion and ion exchange chromatography. Some of the fractions were investigated for adjuvant activity in guinea pigs. The guinea pigs were immunized against foot-and-mouth disease virus serotype 0, and adjuvant activity was estimated as an increase in(More)
Treatment of AKR mice with the saponin Quil A delayed their death in spontaneous leukaemia. In vitro tests did not demonstrate any influence on infection of rat cells with Kirsten sarcoma virus. Quil A in the concentration nanogram/ml doubled the mitogen response of AKR spleen cells to lipopolysaccharide.
Angiopoietin-like protein 4 (ANGPTL4) is a lipoprotein lipase inhibitor that is involved in lipid metabolism and angiogenesis. Animal studies have suggested that the ANGPTL4 protein is modulated by the gut microbiota, possibly through increased concentrations of SCFA, such as C4, found in whole-fat milk or as a result of fermentation of inulin. This study(More)
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