Karsten B Hindsholm

Learn More
OBJECTIVE The purpose of this study was to evaluate the possible cardioprotective effect of sevoflurane versus propofol anesthesia in patients undergoing cardiac surgery. METHODS Ten thousand five hundred thirty-five consecutive single cardiac surgical procedures from 3 cardiac centers were reported to a common registry from 1999 to 2005. The registry was(More)
OBJECTIVES The purpose of this multicentre cohort study was to examine the relationship between antiplatelet therapy (APT) at the time of coronary artery bypass grafting (CABG) and postoperative bleeding complications, transfusion requirements and adverse cardiovascular events. METHODS A matched-pair analysis was carried out on 6350 consecutive patients(More)
BACKGROUND Inotropes used to obtain short-term hemodynamic benefits in cardiac surgery may carry a risk of increased myocardial ischemia and adverse outcomes. This study investigated the association between intra- and postoperative use of inotropes and mortality and postoperative complications. METHODS A historic cohort study using prospective data from(More)
Postoperative hypothermia initiates an increased oxygen demand in the postoperative period and may endanger patients with restricted cardiopulmonary reserves. In order to compare net heat losses and gains, we studied 28 women undergoing hip fracture surgery, using either general anaesthesia or spinal analgesia. The superficial and central temperatures were(More)
This retrospective study was undertaken to evaluate the mortality and morbidity of patients undergoing hip fracture surgery within 12 h of admission, compared with surgery more than 12 h after admission, the patients had no acute medical conditions that required preoperative treatment. Mortality rates were based on survival of the patients up to 1 year(More)
A randomized, double-blind study was carried out on 193 ASA I-II surgical patients to assess the effect of aerosolized lidocaine on sore throat, hoarseness and cough in connection with tracheal intubation. The study group received aerosolized lidocaine 100 mg 2 min before tracheal intubation, using a spray. The control group received no spray. The patients(More)
In a randomized, double-blind study of 40 patients undergoing total abdominal hysterectomy, we have compared continuous subcutaneous infusion (CSCI) of morphine with discontinuous extradural injection of morphine for postoperative analgesia at rest and during cough. The CSCI group received a bolus of morphine 0.1 mg kg-1 i.v. at the end of the operation and(More)
48 simultaneous arterial and venous blood samples from 15 patients with chronic obstructive pulmonary disease (COPD) were evaluated for calculated p50 and measured and calculated 2,3-diphosphoglycerate (DPG) concentration. 23 samples (48%) demonstrated a leftward shift in the calculated in vivo p50, whereas both measured and calculated DPG showed 5% below(More)
We have studied the ability of reflective blankets to reduce net loss of body heat during regional anaesthesia for total hip arthroplasty. Thirty patients were allocated randomly to either the study group (insulated with reflective blankets) or the control group (no reflective blankets). Surgical and operation room draping, theatre temperature and i.v.(More)