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Left Ventricular Systolic Dysfunction Induced by Ventricular Ectopy: A Novel Model for Premature Ventricular Contraction-Induced Cardiomyopathy
Background— Premature ventricular contractions (PVCs) commonly coexist with cardiomyopathy. Recently, PVCs have been identified as a possible cause of cardiomyopathy. We developed a PVC-inducedExpand
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When right may not be right: right bundle-branch block and response to cardiac resynchronization therapy.
Cardiac resynchronization therapy (CRT) in appropriately selected patients has been shown to improve cardiac function, heart failure symptoms, and survival. 1,2 On the basis of results of large,Expand
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Repetitive nonreentrant ventriculoatrial synchrony: An underrecognized cause of pacemaker-related arrhythmia.
Similar to endless loop tachycardia (ELT), repetitive nonreentrant ventriculoatrial synchrony (RNRVAS) is a ventriculoatrial (VA) synchrony pacemaker-mediated arrhythmia. RNRVAS was first describedExpand
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Scar Homogenization in Atrial Fibrillation Ablation: Evolution and Practice.
Atrial fibrillation (AF) ablation has emerged as the preferred rhythm control strategy for symptomatic paroxysmal AF refractory or intolerant to at least one class I or III antiarrhythmic medication.Expand
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Cellular mechanism of premature ventricular contraction-induced cardiomyopathy.
BACKGROUND Frequent premature ventricular contractions (PVCs) are associated with increased risk of sudden cardiac death and can cause secondary cardiomyopathy. OBJECTIVE We sought to determine theExpand
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Arrhythmia-Induced Cardiomyopathy: JACC State-of-the-Art Review.
Arrhythmias coexist in patients with heart failure (HF) and left ventricular (LV) dysfunction. Tachycardias, atrial fibrillation, and premature ventricular contractions are known to trigger aExpand
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A placebo-controlled, double-blind, randomized, multicenter study to assess the effects of dronedarone 400 mg twice daily for 12 weeks on atrial fibrillation burden in subjects with permanent
PurposeDronedarone is a benzofuran derivative with a pharmacological profile similar to amiodarone but has a more rapid onset of action and a much shorter half-life (13–19 h). Our goal was toExpand
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Cardiac pacing in the elderly.
Sinus node disease and atrioventricular block are common etiologies of symptomatic bradyarrhythmias in the elderly and remain the leading indications for permanent pacemaker implantation. In fact,Expand
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Persistent Proarrhythmic Neural Remodeling Despite Recovery From Premature Ventricular Contraction-Induced Cardiomyopathy.
BACKGROUND The presence and significance of neural remodeling in premature ventricular contraction-induced cardiomyopathy (PVC-CM) remain unknown. OBJECTIVES This study aimed to characterizeExpand
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