Karoline Lange

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BACKGROUND Measurement properties of a generic instrument to assess health-related quality of life in patients with chronic pancreatitis have not been described. METHODS We assessed the health-related quality of life in 314 patients with chronic pancreatitis using the generic Medical Outcomes Study Short Form-36 Health Survey. Data were compared with age-(More)
BACKGROUND So far, no techniques are available for primary culture and efficient transfection of human small-intestinal enterocytes, which would provide a valuable tool to investigate intestinal function. METHODS Human small-intestinal biopsy specimens were treated with collagenase and dispase. Resulting crypt units were cultured for several days. Using(More)
CONTEXT Most of the morbidity and mortality from parathyroid cancer is due to PTH-mediated hypercalcemia. Classically, management mainly consists of surgical resection, chemotherapy, and alleviation of hypercalcemia using bisphosphonates and calcium receptor agonists. The use of denosumab in the treatment of parathyroid cancer-mediated hypercalcemia has not(More)
Electronic media play an important role in the everyday lives of children and adolescents and have been shown to be associated with sleep problems. The objective of this study was to assess the associations between time spent using different electronic media and insomnia complaints (IC) in German adolescents with particular respect to gender differences in(More)
To assess whether hearing rehabilitation of older people can be improved by co-operation between the audiology and geriatric departments and the home service, 139 old and frail audiological patients were allocated to three groups with three different fitting procedures: 1) conventional fitting including verification of acoustical gain in the patient's ear;(More)
The purpose of the study was to study the associations of tobacco, alcohol, marijuana, and coffee use and insomnia complaints (IC) in adolescents with special consideration of the influence of coffee consumption on these relationships. 7698 Subjects aged 11–17 years were investigated in a cross-sectional study within the German Health Interview and(More)
Propofol is a hypnotic agent for induction and maintainance of general anaesthesia and it is used for sedation of critically ill intensive care patients. As a rare adverse effect propofol can cause acute pancreatitis. We report a case of post-operative pancreatitis in an otherwise healthy 62-year-old male who was anaesthezised with propofol during an(More)
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