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BACKGROUND The importance of slow-wave sleep (SWS), hallmarked by the occurrence of sleep slow oscillations (SO), for the consolidation of hippocampus-dependent memories has been shown in numerous studies. Previously, the application of transcranial direct current stimulation, oscillating at the frequency of endogenous slow oscillations, during SWS enhanced(More)
OBJECTIVE To determine if ankle muscular strength, flexibility and proprioception can predict ankle injury in college basketball players and to compare ankle injury rates in female and male players. DESIGN AND SETTING In this prospective, correlational study, subjects were tested at the start of the competitive season for ankle joint muscle strength,(More)
The purpose of this study was to investigate the oxygen cost of running barefoot vs. running shod on the treadmill as well as overground. 10 healthy recreational runners, 5 male and 5 female, whose mean age was 23.8±3.39 volunteered to participate in the study. Subjects participated in 4 experimental conditions: 1) barefoot on treadmill, 2) shod on(More)
This study examined the effect of active and passive recovery on lactate concentration and subsequent performance of repeated work bouts in 18 male NCAA Division I ice hockey players. Using a repeated measures design, subjects performed a series of skating tests before and after a 15-minute recovery. The skating test consisted of skating a course for 7(More)
BACKGROUND The aim of this study was to assess the feasibility of administering bizelesin, a cyclopropylpyrroloindole with extraordinarily high potency as a bifunctional DNA-damaging agent and selectivity for specific AT-rich DNA sequences, as a single i.v. bolus injection every 4 weeks in patients with advanced solid malignancies. The study also sought to(More)
The purpose of this investigation was to describe the body composition, peak torque, peak torque ratios, and relative and absolute muscle endurance in the ankle, knee, shoulder, and elbow of 13 female college basketball players. A Cybex(R) II isokinetic dynamometer was used to assess joint torque. Results indicated that 1) these subjects were taller,(More)
A sensitive and specific reversed-phase high-performance liquid chromatographic method was developed for determination of the benzothiazepine calcium channel blocker diltiazem and three of its main metabolites in human plasma. A solid-phase extraction method (C18) is described for isolating diltiazem and the metabolites N-demethyl-diltiazem (M(A)),(More)
BACKGROUND The objective of this study was to examine the effects of angiotensin II receptor blocker losartan versus the calcium channel blocker amlodipine on proteinuria, renal haemodynamics, glomerular sieving and tubular function in hypertensive patients with non-diabetic nephropathy. METHODS The study design was a prospective, double blind, placebo(More)
To assess sympathetic system function after hemispheric brain infarction rostral to the hypothalamus we investigated 24 patients with infarction in the territory of the middle cerebral artery. Anisocoria and basal lacrimal gland secretion were determined. The ninhydrin test was performed and the sympathetic skin response recorded in both hands and feet. The(More)
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