Karol Makowski

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OBJECTIVES Clinical significance of, and the need for, treatment in subclinical hyperthyroidism (sHT) is still a matter of debate. The aim of the study was to assess the impact of sHT on echocardiographic parameters. DESIGN Patients with endogenous sHT of nonautoimmune origin underwent full echocardiographic assessment at diagnosis and after restoring(More)
AIMS The aims of the study were (i) to assess the characteristics of patients selected for atrial fibrillation (AF) ablation as first-line therapy, (ii) to identify current clinical criteria for such a strategy, and (iii) to analyse the outcome compared with patients who had failure of antiarrhythmic drug (AAD) therapy prior to ablation. METHODS AND(More)
BACKGROUND Analysis of pathophysiological mechanisms responsible for vaso-vagal reaction reveals a close relationship between neurocardiogenic syncope and the preceding abnormalities of autonomic nervous system (ANS). Therefore, the interest in the assessment of heart rate variability (HRV) for detecting and establishing therapy in patients with syncope due(More)
BACKGROUND Although beta-blockers are frequently used in order to prevent the recurrence of vasovagal syncope, the efficacy of this treatment is difficult to determine. OBJECTIVES To determine if the result of a tilt test with an intravenously administered beta-blocker can predict the long-term efficacy of beta-blockade. METHODS The study group(More)
BACKGROUND The impact of subclinical hyperthyroidism (sHT) on the cardiovascular system still needs to be elucidated. The aim of the study was to prospectively assess blood pressure (BP), variability in heart rate, and the prevalence of arrhythmias in patients with sHT, both before and after they are restored to the euthyroid state. METHODS The study(More)
BACKGROUND Although beta blockers are frequently used for the prevention of recurrences of vaso-vagal syncope, the prediction of the long-term efficacy of this treatment is difficult. AIM To assess whether the result of tilt testing with an intravenous beta blocker can predict the long-term efficacy of beta blockade. METHODS The study group consisted of(More)
BACKGROUND Patients with essential hypertension (EH) and left ventricular hypertrophy (LVH) have an increased risk of cardio-vascular complications. Alterations in the autonomic nervous system (ANS) activity may play a role in the development of serious cardiac arrhythmias and mortality in these patients. AIM To examine the activity of ANS in patients(More)
UNLABELLED The disproportion between absence of clinical manifestations of circulatory system involvement and serious lesions in the heart found on post mortem examinations, more frequently diagnosed congestive circulatory failure and also higher mortality rate of patients with rheumatoid arthritis (RA), encouraged the authors to study the subject. THE(More)
INTRODUCTION Tilt testing (TT) is a well-established tool in the diagnosis of syncope. However, it is time-consuming. Therefore, identification of parameters that could shorten the duration of TT is desirable. AIM To identify and assess the usefulness of early haemodynamic parameter changes in prediction of the tilt test results in a group of patients(More)
BACKGROUND Microvolt T-wave alternans (MTWA) is a promising method for noninvasive assessment of arrhythmic risk. Recent studies have shown good immediate reproducibility of T-wave alternans. Little is known about it during the long term. The aim of the study was to prospectively evaluate the long-term reproducibility of MTWA in a group of patients after(More)