This paper presents literature data about effects of low-intensity variable electromagnetic fields on the neuroendocrine system of experimental animals. We mostly paid attention to electromagnetic fields frequently found in our environment, in technological processes, even in our everyday life. This study shows that the regulatory systems (nervous and… (More)
Diabetes mellitus type 1 (T1D) is a complex disease resulting from the interplay of genetic, epigenetic, and environmental factors. Recent progress in understanding the genetic basis of T1D has resulted in an increased recognition of childhood diabetes heterogeneity. After the initial success of family-based linkage analyses, which uncovered the strong… (More)
Most cases of juvenile-onset diabetes (JOD) are diagnosed as type 1 diabetes (T1D), for which genetic studies conducted in outbred Caucasian populations support the concept of multifactorial inheritance. However, this view may be partly challenged in particular population settings. In view of the suggestive evidence for a high prevalence of Wolfram syndrome… (More)
The metabolic syndrome (MetS) is a polygenic multifactorial metabolic disorder with strong socioeconomic influence. MetS has became a worldwide epidemic, that directly increases the risk of cardiovascular diseases and type 2 diabetes mellitus. The human apoE gene, coding Apolipoprotein E, has three common polymorphisms in human population: e2, e3 and e4,… (More)
INTRODUCTION Carbon nanotubes (CNTs) are a distinct molecular form of carbon atoms. They were described in 1991 by Sumio Lijima as a tube-shaped, well-ordered, flat network of carbon (1). There are two major classes of carbon nanotubes: single-walled nanotubes (SWNT) composed of a single graphite layer with diameters ranging from 1 to 10 nm and multi-walled… (More)
abstract Diabetes mellitus type 1 (T1D) is a complex disease resulting from the interplay of genetic, epigenetic, and environmental factors. Recent progress in understanding the genetic basis of T1D has resulted in an increased recognition of childhood diabetes heterogeneity. After the initial success of family-based linkage analyses, which uncovered the… (More)
Background The medicines for peptic ulcer and gastro-esophageal reflux disease (ATC subgroup A02B) are among the most commonly prescribed class of drugs. The aim of this study was to analyze the pattern of consumption of histamine H 2 receptor antagonists (H 2 RAs) and proton pump inhibitors (PPIs) in Serbia in 2010 in comparison with Croatia and Sweden.… (More)
Background TGR5 (M-BAR, GPBAR or GPR131) is a plasma membrane bound , G protein-coupled receptor for bile acids, expressed in many human cells. The aim of this study was to describe that targeting TGR5 could provide an exciting new pharmacological approach to improve different aspects of the metabolic syndrome in humans.