Karlijn de Nie

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OBJECTIVE  To identify and characterise non-specific immunological effects after routine childhood vaccines against BCG, measles, diphtheria, pertussis, and tetanus. DESIGN  Systematic review of randomised controlled trials, cohort studies, and case-control studies. DATA SOURCES  Embase, PubMed, Cochrane library, and Trip searched between 1947 and(More)
Neisseria meningitidis recruits host human complement inhibitors to its surface to down-regulate complement activation and enhance survival in blood. We have investigated whether such complement inhibitor binding occurs after vaccination with native outer membrane vesicles (nOMVs), and limits immunogenicity of such vaccines. To this end, nOMVs reactogenic(More)
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