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  • Madeleine C. Chalfant, Karl W Barber, Sapan Borah, David Thaller, C Patrick Lusk
  • Biology, Medicine
  • Molecular biology of the cell
  • 2019 (First Publication: 1 March 2019)
  • DYT1 dystonia is caused by an in-frame deletion of a glutamic acid codon in the gene encoding the AAA+ ATPase TorsinA (TorA). TorA localizes within the lumen of the nuclear envelope/endoplasmicContinue Reading
  • Brandon M Gassaway, Max C. Petersen, +7 authors Jesse Rinehart
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2018 (First Publication: 18 September 2018)
  • Insulin resistance drives the development of type 2 diabetes (T2D). In liver, diacylglycerol (DAG) is a key mediator of lipid-induced insulin resistance. DAG activates protein kinase C ε (PKCε),Continue Reading
  • Karl W Barber, Jesse Rinehart
  • Biology, Medicine
  • Nature chemical biology
  • 2018 (First Publication: 1 March 2018)
  • Post-translational modifications (PTMs) are ubiquitous in all forms of life and often modulate critical protein functions. Recent chemical and biological advances have finally enabled scientists toContinue Reading