• Publications
  • Influence

Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications (all current information on this profile has been aggregated automatically from publisher and metadata sources).
  • Bernd Friedgen, Reinhard Wölfel, Karl-Heinz Graefe
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 1996
  • To study the effects of inhibition of catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO) on the removal of circulating catecholamines, anaesthetized rabbits were infused for 120 min withContinue Reading
  • Bernd Friedgen, Reinhard Wölfel, Hermann Russ, Edgar Schömig, Karl-Heinz Graefe
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 1996 (First Published: 1 August 1996)
  • As selective inhibitors of the extraneuronal monoamine uptake system (uptake2) suitable for in-vivo studies were not available, the question of whether uptake2 plays a definite role in vivo isContinue Reading
  • Reinhard Wölfel, Karl-Heinz Graefe
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 1992 (First Published: 1 February 1992)
  • SummaryThe aim of the present study was to answer the question whether amines other than 5-hydroxytryptamine (5-HT) and tryptamine act as substrates of the platelet 5-HT transporter. To this end, aContinue Reading
  • Bernd Friedgen, Thomas Halbrügge, Karl-Heinz Graefe
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 1993 (First Published: 1 February 1993)
  • SummaryThe present study, carried out in anaesthetized rabbits, aimed at determining the effects of catechol-O-methytransferase (COMT) inhibition on the plasma kinetics of infusedContinue Reading
  • Thomas Halbrügge, Bernd Friedgen, Josef Ludwig, Karl-Heinz Graefe
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 1993 (First Published: 1 February 1993)
  • SummaryThe purpose of this study was to elucidate the finding of Friedgen et al. (1993b) that catechol-O-methyltransferase (COMT) inhibition is much more effective in increasing the plasmaContinue Reading