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Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor.
A series of dipyridodiazepinones have been shown to be potent inhibitors of human immunodeficiency virus-1 (HIV-1) reverse transcriptase (RT). One compound, BI-RG-587, had a Ki of 200 nanomolar forExpand
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Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by the dipyridodiazepinone BI-RG-587.
The dipyridodiazepinone human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor BI-RG-587 was tested for its ability to inhibit HIV-1 replication in both acutely andExpand
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Challenges and potential for RNA nanoparticles (RNPs).
The current research of our group focuses on delivery of oligonucleotides and gene vaccines targeted against infectious disease and cancer. Recently we reported a strategy for associating DNA to goldExpand
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Indications for penile revascularization and long‐term results
Summary. The purpose of this study was to analyse long‐term results of penile revascularization using Hauri's method in 124 patients with a mean follow‐up of 54 months. Of 176 patients undergoingExpand
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C -Nucleosides and Related Compounds. IV. The Synthesis and Chemistry of D,L-2,5-Anhydroallose Derivatives
Methyl β-nitroacrylate (1) reacted with furan to give the corresponding Diels–Alder adduct, which was converted to D,L-3,4-di-O-isopropylidene-2,5-anhydroallose (9) in a five-step sequence in 14%Expand
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Die mikrochirurgische testikuläre Denervierung als Therapieoption der chronischen Testalgie
ZusammenfassungDie chronische Testalgie repräsentiert ein sowohl diagnostisch als auch therapeutisch problematisches urologisches Krankheitsbild. Die Erfolgsraten der konservativen und der operativenExpand
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3-hydroxysydnone imines
Abstract Condensation of aldehydes, hydroxylamine and cyanide resulted in the formation of Mannich bases, which were nitrosated, to form 3-hydroxysydnone imines on acid treatment. A novel mesoionicExpand
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