Karl G. Rosen

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OBJECTIVE To assess whether intrapartum acidosis affects specific components of fetal heart rate variability. DESIGN Prospective clinical study. SETTING Twelve Nordic delivery units. SUBJECTS Fetal heart rate variability was studied in 334 fetuses divided into two groups according to cord pH value: the acidotic group (cord arterial pH < 7.05 at birth,(More)
This study examines a novel methodology for continuous fetal heart rate variability (FHRV) assessment in a non-stationary intrapartum fetal heart rate (FHR). The specific aim was to investigate simple statistics, dimension estimates and entropy estimates as methods to discriminate situations of low FHRV related to non-reassuring fetal status or as a(More)
Waveform analysis of the fetal ECG for fetal surveillance is regaining widespread interest. This paper presents our present knowledge on ST waveform analysis during human labour. A unipolar scalp lead with the maternal thigh as reference makes it possible to identify the T wave and at the same time decrease signal noise. The development of an ECG analyser(More)
Fetal ECG waveform analysis as an adjunct to electronic fetal monitoring (EFM) has developed over the last 3 decades. From a multitude of potential parameters, ST waveform analysis has been documented to provide the information required to shift EFM from a screening device to a diagnostic tool that meets the standards of evidence-based medicine. This(More)
OBJECTIVE Cardiotocography plus automatic ST analysis of the fetal electrocardiography has been shown recently to reduce both the operative delivery rate for fetal distress and the cord artery metabolic acidosis rate. The purpose of this study was to analyze findings that were related to cases with a complicated/adverse neonatal outcome in the Swedish(More)
BACKGROUND Intrapartum fetal hypoxia remains an important cause of death and permanent handicap and in a significant proportion of cases there is evidence of suboptimal care related to fetal surveillance. Cardiotocographic (CTG) monitoring remains the basis of intrapartum surveillance, but its interpretation by healthcare professionals lacks reproducibility(More)
OBJECTIVE To identify the distribution of carbon dioxide tension (pCO(2) ) relative to pH in validated umbilical cord acid-base data. DESIGN Observational study. SETTING European hospital labour wards. POPULATION Data for 36,432 term newborns were obtained from three sources: two trials of fetal monitoring with electrocardiography (ECG; the Swedish(More)
INTRODUCTION Since its introduction into clinical use, the efficacy of electronic fetal heart rate (FHR) monitoring (EFM) has been questionable. This has been due partly to the marked variation in interpretation of the FHR pattern and subsequent decisions for obstetric intervention, (e.g., the need for prompt delivery). Current application of EFM is limited(More)
To conduct a controlled trial to test the ability of a newly developed electrostatic air cleaning technology (EAC) to improve Indoor Air Quality (IAQ) as defined by levels of airborne particles and to investigate the potential to reduce non-attendance rates due to illness among children in two Swedish day care centres. The EAC technology was shown to(More)
Previous studies from this laboratory have demonstrated early and progressive alterations in the ST-T period of the fetal and neonatal electrocardiogram in relation to asphyxia. The aims of the present study were to investigate the metabolic background of these hypoxic ECG changes by means of serial myocardial biopsies in fetal lambs, relating these changes(More)