Karl Erik Edberg

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ABSTRACT: We assessed pulmonary function in 14 mechanically ventilated newborn very low birth weight infants with idiopathic respiratory distress syndrome by means of a face-out, volume displacement body plethysmograph and nitrogen washout analyses. Specially designed computer programs were used for calculations of lung volumes, ventilation, gas mixing(More)
We have studied the effects on lung volume, respiratory mechanics and ventilation during the first hours after instillation of 60 mg/kg of human surfactant into the trachea of 4 very preterm, newborn infants with severe IRDS under mechanical ventilation. Measurements were made with a "face-out" body plethysmograph and a modified nitrogen wash-out method. In(More)
Twelve patients (median age 3.8 months) with pulmonary hypertension in the postoperative period after congenital heart surgery on cardiopulmonary bypass were given inhaled nitric oxide. Effects on cardiovascular and respiratory systems were measured. Mean pulmonary artery pressure decreased from 33+/-2 to 28+/-2 mmHg (p < 0.001) and arterial oxygen tension(More)
OBJECTIVES To assess patient safety and to evaluate operator acceptance to the technology of neurally adjusted ventilatory assist. DESIGN A within-patient crossover study. SETTING A ten-bed tertiary care university hospital pediatric intensive care unit. PATIENTS A total of 21 mechanically ventilated infants and children aged 2 days to 15 yrs(More)
OBJECTIVE We aimed to evaluate the efficacy, morphine requirements and side effects in patients managed with patient-controlled analgesia postoperatively. METHODS Eighty-seven patients, 7 to 22 (median 14) years of age, after orthopedic, abdominal or thoracic surgery, were studied retrospectively. All patients had a preset standard continuous morphine(More)
We have studied lung function in 4 intubated and ventilated newborn infants with IRDS (birth-weights 1.1-1.47 kg, gest. age 26-29 w) immediately before and then repeatedly over 4 hours after instillation of human surfactant (100 mg/kg) into the endotrachealtubes. The infants were ventilated with max. insufflation pressures of 24-33 cml 120 and 4-10 cml 120(More)
Bronchoscopy has been used for evaluation of the potential problems of the airways and for investigation the bronchial specimens for diagnostic purposes. Recent technical advances result in performing this procedure at the bedside manner and in critically ill patients. We have performed 150 bronchoscopy during last three years on 1362 pediatric patients(More)
METHODS Fourteen children aged 4-15 months were studied after corrective cardiac surgery. Heart rate was increased by 20% with an external pacemaker. Cardiac output (CO) was measured with thermodilution. Oxygen saturation was measured in systemic artery (SaO2), central vein (ScvcO2) and pulmonary artery (SvO2). Inspiratory to endtidal oxygen difference(More)
Extracorporeal membrane oxygenation was used as a bridge for three infants with complicated long segment congenital tracheal stenosis to tracheal homograft transplantation with cadaveric tracheal homograft and for one child, with an extensive traumatic tracheal laceration caused by aspiration of a sharp foreign body, to definitive tracheal repair. In all(More)