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Altered Synaptic Properties During Integration of Adult-Born Hippocampal Neurons Following a Seizure Insult

• Johanna S. Jackson, Deepti A Chugh, +4 authors Christine T. Ekdahl
• PloS one
• 2012

Pathological conditions affect several stages of neurogenesis in the adult brain, including proliferation, survival, cell fate, migration, and functional integration. Here we explored how a… (More)

Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3

• Marta Pérez-Alcázar, Jonny Daborg, +9 authors Marcela Pekna
• Experimental Neurology
• 2014

Previous work implicated the complement system in adult neurogenesis as well as elimination of synapses in the developing and injured CNS. In the present study, we used mice lacking the third… (More)

Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution.

• Katarina Johansson, Marcus Cebula, +5 authors Elias S. J. Arnér
• Antioxidants & redox signaling
• 2017

AIM Many transcription factors with importance in health and disease are redox regulated. However, how their activities may be intertwined in responses to redox-perturbing stimuli is poorly… (More)

Variability in C-type lectin receptors regulates neuropathic pain-like behavior after peripheral nerve injury

• Cecilia A. Dominguez, Karl E. Carlström, +4 authors Fredrik Piehl
• Molecular pain
• 2014

INTRODUCTION Neuropathic pain is believed to be influenced in part by inflammatory processes. In this study we examined the effect of variability in the C-type lectin gene cluster (Aplec) on the… (More)

High Glutathione-S-transferase 4 alpha expression promotes nerve cell survival in neurodegenerative disorders

• Karl E. Carlström, Faiez Al Nimer, Mikael Ström, Fredrik Piehl
• Journal of Neuroimmunology
• 2014

Reactive oxygen species (ROS) are major contributors to neuropathology in both Multiple sclerosis and other neurodegenerative disorders. ROS are small molecules with unpaired electrons, making them… (More)

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