Karl Burgin

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The use of fusions between dendritic cells (DCs) and tumor cells as vaccines has been proved very effective in stimulating antitumor immune responses, both in animal studies and in early human clinical trials. Because of the difficulty of purifying the hybrid cells from the fusion, fusion mixtures were used in these studies. Recently, we developed a(More)
BACKGROUND AND PURPOSE Organic nitrates represent a group of nitrovasodilators that are clinically used for the treatment of ischemic heart disease. With the present studies we synthesized and characterized new organic nitrate hybrid molecules. Compounds CLC-1265 (valsartan mononitrate) and CLC-1280 (valsartan dinitrate) are derivatives of the angiotensin(More)
BACKGROUND/AIMS Organic nitrates represent a group of nitrovasodilators that are clinically used for the treatment of ischemic heart disease. The new compound CLC-3000 is an aminoethyl nitrate (AEN) derivative of pioglitazone, a thiazolidinedione antidiabetic agent combining the peroxisome proliferator-activated receptor γ agonist activity of pioglitazone(More)
An extended Benzi-Dellar lattice Boltzmann equation scheme [R. Benzi, S. Succi, and M. Vergassola, Europhys. Lett. 13, 727 (1990)EULEEJ0295-507510.1209/0295-5075/13/8/010; R. Benzi, S. Succi, and M. Vergassola, Phys. Rep. 222, 145 (1992)PRPLCM0370-157310.1016/0370-1573(92)90090-M; P. J. Dellar, Phys. Rev. E 65, 036309(More)
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