Karine Pernet-Gallay

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The terminal cisternae represent one of the functional domains of the skeletal muscle sarcoplasmic reticulum (SR). They are closely apposed to plasma membrane invaginations, the T-tubules, with which they form structures called triads. In triads, the physical interaction between the T-tubule-anchored voltage-sensing channel DHPR and the SR calcium channel(More)
  • Deloulme Jc, Boulan B, Mire E, Xue J, Jany M Maucler, Deparis Aa +21 others
  • 2016
Title of project: MAP6, LIM Kinases and actin dynamic in dendritic spines Objectives (3 lines max): MAP6/STOP is a key regulator of actin dynamic in the dendritic spines. LIM kinases are also key regulators of actin stability in spines. The project will aim at analyze possible regulation of MAP6 properties by LIM kinase and the consequences on actin(More)
Vascular endothelial growth factor (VEGF) is known to be required for the action of antidepressant therapies but its impact on brain synaptic function is poorly characterized. Using a combination of electrophysiological, single-molecule imaging and conditional transgenic approaches, we identified the molecular basis of the VEGF effect on synaptic(More)
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