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OBJECTIVES To assess the effect of biotherapies vs placebo on fatigue in two situations: inadequate response to conventional treatments (IR-DMARD) and inadequate response to anti-TNF (IR-anti-TNF) in… (More)
PURPOSE IL-8 and its murine equivalent keratinocyte chemoattractant (Kc), chemokines produced by chondrocytes, contribute to the pathophysiology of osteoarthritis. However, the mechanisms leading to… (More)
The efficacy of anakinra on both RA-related symptoms and structural damage has been demonstrated in several randomized controlled trials. However, its interest seems limited with regards to other… (More)
OBJECTIVES Fatigue is an important aspect of spondyloarthritis (SpA). However the influencing factors of fatigue in SpA are unclear. The objective of this study was to explore if fatigue is related… (More)
Background Monoclonal gammapathy of undetermined significance (MGUS) is premalignant plasma-cell disorder. Its prevalence is about 3.2% of the general population older than 50 years. In patients with… (More)
Resume Objectif L’interleukine-8 (IL-8) et son equivalent murin keratinocyte chemoattractant (Kc), chimiokines produites par les chondrocytes, contribuent a la physiopathologie de l’arthrose.… (More)