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DNA Damage, Somatic Aneuploidy, and Malignant Sarcoma Susceptibility in Muscular Dystrophies

• Wolfgang M. Schmidt, Mohammed Helal Uddin, +7 authors Reginald E. Bittner
• PLoS genetics
• 2011

Albeit genetically highly heterogeneous, muscular dystrophies (MDs) share a convergent pathology leading to muscle wasting accompanied by proliferation of fibrous and fatty tissue, suggesting a… (More)

Accumulation of very long-chain fatty acids does not affect mitochondrial function in adrenoleukodystrophy protein deficiency.

• Iris Oezen, Walter Rossmanith, +6 authors Johannes Berger
• Human molecular genetics
• 2005

X-linked adrenoleukodystrophy (X-ALD, OMIM 300100) is a severe inherited neurodegenerative disease, associated with the accumulation of very long-chain fatty acids (VLCFA). The recent unexpected… (More)

Growth inhibition by dehydrothyrsiferol - a non-Pgp modulator, derived from a marine red alga - in human breast cancer cell lines.

• Martina K Pec, Karin Moser-Thier, J. J. Fernández, Miguel Souto, Erwin Kubista
• International journal of oncology
• 1999

The novel marine terpenoid dehydrothyrsiferol (DHT) has been isolated from a Canarian red alga Laurencia viridis sp. nov (Ceramiales, Rhodomelaceae) (1). Its cytotoxicity against three human breast… (More)

Inhibitory effects of a novel marine terpenoid on sensitive and multidrug resistant KB cell lines.

• Martina K Pec, Minea Hellan, Karin Moser-Thier, J. J. Fernández, Miguel Souto, Erwin Kubista
• Anticancer research
• 1998

Mechanisms of growth inhibition by the novel marine compound dehydrothyrsiferol (DHT) were investigated in a sensitive and an MDR+ human epidermoid cancer cell line. DHT was found to circumvent… (More)

Induction of apoptosis in estrogen dependent and independent breast cancer cells by the marine terpenoid dehydrothyrsiferol.

• Martina K Pec, Amable Aguirre, +5 authors J Villar
• Biochemical pharmacology
• 2003

Breast cancer (BCA) represents the highest incidence of death in 35- to 60-year-old women. Above all, hormone unresponsive BCA is still associated with poorer prognosis than hormone receptor… (More)

Characterization of S-layers from mesophilic bacillaceae and studies on their protective role towards muramidases

• Margit Sára, Karin Moser-Thier, Ursula Kainz, Uwe Sleytr
• Archives of Microbiology
• 2004

The structure of the S-layers from eight mesophilic Bacillaceae was investigated by freeze-etching of whole cells. The S-layer lattices from Bacillus alvei CCM 2051 and B. circulans CCM 1048… (More)

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