Karin Kühner

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Using CRISPR/Cas9, it is possible to target virtually any gene in any organism. A major limitation to its application in gene therapy is the size of Cas9 (>4 kb), impeding its efficient delivery via recombinant adeno-associated virus (rAAV). Therefore, we developed a split-Cas9 system, bypassing the packaging limit using split-inteins. Each Cas9 half was(More)
Two studies tested the multiple resources model of information processing using tachistoscopically lateralized input. In Exp. 1 37 normal, dextral subjects, 18 men aged 18/21 yr. and 19 women aged 18/22 yr. responded manually to a visuo-spatial and verbal dual-task presented simultaneously to left and right brain or nonlaterally. Both men and women tended(More)
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