Karin Edvardsson

Learn More
There is epidemiological, animal and in vitro evidence that estrogen receptor β (ERβ) can mediate protective effects against colon cancer, but the mechanism is not completely understood. Previous research has indicated critical pathways whereby ERβ acts in an antitumorigenic fashion. In this study, we investigate ERβ's impact on the microRNA (miRNA) pool in(More)
In decision theory goals are usually taken as given inputs to the analysis, and the focus is on finding the most efficient means to achieve the goals. But where goals are set with the purpose of achieving them, it is important to know what properties they should possess in order to be successful (or achievement-inducing). Four such properties (or(More)
Breast cancers are sensitive to hormones such as estrogen, which binds to and activates estrogen receptors (ER) leading to significant changes in gene expression. microRNAs (miRNA) have emerged as a major player in gene regulation, thus identification of miRNAs associated with normal or disrupted estrogen signaling is critical to enhancing our understanding(More)
INTRODUCTION Mammary stem cells are bipotential and suggested to be the origin of breast cancer development, but are elusive and vaguely characterized. Breast tumors can be divided into subgroups, each one requiring specific treatment. To determine a possible association between mammary stem cells and breast cancer, a detailed characterization of the(More)
BACKGROUND In vivo models of uremia are important tools to study numerous aspects of acute and chronic kidney disease. Mouse models are pivotal because most genetically engineered animal models are mice, which allow dissecting the impact of selected target genes in renal failure. Adenine-based protocols to induce renal failure are available in rats, but(More)
Access to the published version may require subscription. Abstract The accurate measurement of a vehicle's velocity is an essential feature in adaptive vehicle activated sign systems. Since the velocities of the vehicles are acquired from a continuous wave Dop-pler radar, the data collection becomes challenging. Data accuracy is sensitive to the calibration(More)
In all the Nordic countries unbound or thin sealed road surfaces are common. Low traffic volume roads include all roads with a traffic volume of up to 1,000 vehicles per day. Approximately 75% of the total Swedish government administered road network is low volumed. For the municipal road network, the corresponding figure is 70%. In addition, the whole(More)
  • 1