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Web Usage Mining (WUM) aims to extract navigation usage patterns from Web server logs. Mining algorithms yield usage patterns, but finding the ones that constitute new and interesting knowledge in the domain remains a challenge. Typically, analysts have to deal with a huge volume of pattern, from which they have to retrieve the potentially interesting one(More)
OBJECTIVES The kinetics of drug absorption for nasally administered drugs are often studied using excised mucosal tissue. To avoid the disadvantages of animal experiments, cellular in-vitro models have been established. This study describes the optimization of culture conditions for a model based on the RPMI 2650 cell line, and an evaluation of this model's(More)
BACKGROUND Free peritoneal tumor cells (FPTCs) are an independent prognostic factor in patients undergoing curative resection for gastric carcinoma. Whether neoadjuvant chemotherapy (NAC) can eliminate FPTCs in the peritoneal lavage remains unclear. The aim of the study was to determine the effect of NAC on FPTCs. METHODS From 1994 to 2000, data from a(More)
UNLABELLED Previous studies demonstrated that chemotherapy-induced changes in tumor glucose metabolism measured with (18)F-FDG PET identify patients who benefit from preoperative chemotherapy and those who do not. The prognosis for chemotherapy metabolic nonresponders is poorer than for metabolic responders. Therefore, we initiated this prospective trial to(More)
Web usage mining (WUM) is the process of extracting navigation behaviour patterns that allow analysing users' interactions with Web-based environments. We discuss the impact of developing the WUM preprocessing phase according to concepts, problems and goals specific to Web-based learning environments. We present a tool prototype that automates typical tasks(More)
A major advantage of Service-Oriented Architectures (SOA) is composition and coordination of loosely coupled services. Because the development lifecycles of services and clients are decoupled, multiple service versions have to be maintained to continue supporting older clients. Typically versions are managed within the SOA by updating service descriptions(More)
PURPOSE The MUNICON trial confirmed prospectively the usefulness of early response evaluation by 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography (FDG-PET) . Metabolic responders (R) showed initially a higher FDG uptake compared with nonresponders (p = 0.018). An association of the vascular endothelial growth factor (VEGF) 936C>T polymorphism(More)